Profhilo is a distinctive skin booster that stands out in the realm of aesthetic treatments for its innovative approach to skin rejuvenation and anti-aging. Unlike traditional fillers, Profhilo offers bio-remodeling by improving the skin's structure and hydration from within.

This treatment has garnered attention for its effectiveness in enhancing skin texture, elasticity, and overall radiance without altering facial contours. 


Profhilo is an injectable skin treatment made from one of the highest concentrations of hyaluronic acid (HA) available on the market. It is designed to treat skin laxity by stimulating the production of collagen and elastin, two proteins crucial for maintaining skin's firmness and elasticity.

Profhilo is not a dermal filler in the traditional sense; it doesn't add volume or change the shape of the face. Instead, it rejuvenates the skin, resulting in a more youthful and hydrated appearance.

What Is Profhilo

The Science Behind Profhilo

Profhilo represents a significant advancement in non-surgical aesthetic treatments, leveraging the bio-remodeling capabilities of hyaluronic acid (HA) to improve skin texture, elasticity, and hydration. The science behind Profhilo is rooted in its unique formulation and action mechanism, which distinguish it from traditional dermal fillers and other HA-based products. Here's an in-depth look at the scientific principles that underpin Profhilo's effectiveness:

Unique Formulation of Hyaluronic Acid

  • High Concentration and Purity: Profhilo contains one of the highest concentrations of HA available—64 mg in 2 ml—without any chemical cross-linking agents besides thermal bonding. This results in a highly pure and stable product designed for deep tissue remodeling rather than just surface-level hydration or volume addition.
  • Thermal Cross-Linking Technology: Profhilo utilizes a patented thermal cross-linking process known as NAHYCO™ technology, which creates a stable hybrid cooperative complex of high molecular weight (HMW) and low molecular weight (LMW) hyaluronic acid. This process enhances the longevity and performance of HA in the skin.

Mechanism of Action

  • Hydration and Bio-Remodeling: The LMW HA in Profhilo provides intense hydration by binding water molecules in the skin, improving tissue quality and skin appearance. The HMW HA forms a stable scaffold in the skin, promoting the longevity of the treatment effects.
  • Stimulation of Collagen and Elastin: Profhilo uniquely stimulates the production of four different types of collagen (types I, III, IV, and VII) and elastin. This is attributed to the slow release of HA, which activates fibroblasts and keratinocytes, enhancing skin elasticity, firmness, and supporting tissue repair and remodeling.

Bio-Stimulation of Skin Cells

  • Dual Action: Beyond its hydrating properties, Profhilo induces a bio-stimulation effect, activating skin cells without the need for added chemical agents. This dual action—hydration plus stimulation—results in improved skin quality from within, making the skin look and feel younger and healthier.
  • Release of Growth Factors: The interaction of HA with skin cells also promotes the release of growth factors, further aiding in skin repair, reducing inflammation, and encouraging cellular rejuvenation.

Clinical Effects and Benefits

  • Improved Skin Laxity: Clinical studies and patient reports indicate significant improvements in skin laxity and tightness after Profhilo treatment, particularly in areas prone to early signs of aging, such as the face, neck, and hands.
  • Enhanced Skin Texture: Patients often report a noticeable improvement in skin texture, with increased smoothness and a reduction in fine lines and imperfections.
  • Long-Lasting Hydration: The deep hydration provided by Profhilo leads to a more radiant and dewy complexion, with effects lasting up to six months after a complete treatment cycle.

Safety Profile

  • Biocompatibility: Given that HA is a naturally occurring substance in the skin, Profhilo is well-tolerated, with a low risk of adverse reactions. Its unique formulation without synthetic cross-linking agents further reduces the likelihood of complications.

Benefits of Profhilo Treatment

Profhilo treatment offers a unique approach to skin rejuvenation, combining deep hydration with the stimulation of collagen and elastin production to improve skin quality and appearance. Its benefits stem from its innovative formulation of hyaluronic acid, which is designed not just to add volume but to remodel aging and sagging tissue. Here are the key benefits of Profhilo treatment:

1. Improved Skin Hydration

  • Profhilo delivers hyaluronic acid deep into the skin, significantly improving hydration levels. This results in plumper, more dewy, and intensely moisturized skin, addressing issues of dryness and dehydration.

2. Enhanced Skin Elasticity and Firmness

  • By stimulating the production of collagen and elastin, Profhilo enhances skin elasticity and firmness. This can lead to a noticeable reduction in skin laxity, making the skin appear tighter and more youthful.

3. Reduced Fine Lines and Wrinkles

  • The bio-remodeling action of Profhilo helps to smooth out fine lines and wrinkles, particularly those caused by skin dehydration and loss of elasticity. The result is a smoother, fresher skin surface.

4. Improved Skin Texture and Tone

  • Profhilo treatment can lead to an improved skin texture, making the skin feel softer and appear more even. It can also help to improve the skin's tone, contributing to a more radiant and healthy-looking complexion.

5. Minimal Downtime

  • Unlike more invasive cosmetic procedures, Profhilo offers the advantage of minimal downtime. Patients can usually resume their normal activities immediately after treatment, making it a convenient option for those with busy lifestyles.

6. Natural-Looking Results

  • Profhilo provides natural-looking rejuvenation, enhancing the skin's intrinsic properties without altering facial contours or expressions. This subtlety makes it an attractive option for those seeking modest, natural improvements.

7. Versatile Treatment Areas

  • While commonly used for facial rejuvenation, Profhilo can also be effectively applied to other areas of the body, including the neck, décolletage, hands, and arms, where skin may show signs of aging or dehydration.

8. Long-lasting Effects

  • The effects of Profhilo treatment can last up to six months, depending on individual factors such as age, skin condition, and lifestyle. Maintenance treatments can help to prolong these benefits.

9. Suitable for a Wide Range of Patients

  • Profhilo is suitable for patients of various ages looking to combat the signs of skin aging or to proactively maintain their skin's hydration and elasticity. It's particularly beneficial for those noticing the first signs of skin aging or those seeking to enhance the quality of their skin.

10. Safety and Tolerability

  • Profhilo's formulation is biocompatible, owing to the natural presence of hyaluronic acid in the skin. It has a strong safety profile, with adverse reactions being rare and generally mild when they do occur.

Profhilo vs. Other Hyaluronic Acid Treatments

Profhilo represents a unique approach within the range of hyaluronic acid (HA)-based treatments, differing significantly from traditional HA fillers and other HA-based skin therapies in its composition, mechanism of action, and intended outcomes. Understanding these differences can help in choosing the most appropriate treatment for specific skin concerns. Here's a comparison of Profhilo with other HA treatments:

Profhilo vs. Traditional HA Dermal Fillers

  • Composition: Profhilo is composed of a unique mixture of low and high molecular weight hyaluronic acid, without any chemical cross-linking agents other than thermal bonding. This contrasts with traditional HA fillers, which typically consist of a single form of HA that is chemically cross-linked to enhance its stability and longevity in the skin.

  • Mechanism of Action: Profhilo acts by bio-remodeling the skin, improving hydration, elasticity, and firmness through the stimulation of collagen and elastin production. Traditional HA fillers, in contrast, primarily work by adding volume to specific areas of the face, such as cheeks, lips, and nasolabial folds, directly lifting and filling wrinkles and sagging skin.

  • Treatment Areas and Outcomes: Profhilo is designed for overall skin rejuvenation, targeting skin laxity and texture over a broad area, rather than correcting specific lines or restoring volume. It's particularly effective in areas like the face, neck, hands, and décolletage. HA fillers are used for targeted volume augmentation and wrinkle reduction, offering more localized improvements.

Profhilo vs. Skin Hydration Boosters

  • HA Concentration and Properties: Profhilo boasts one of the highest concentrations of HA available, utilizing a stabilizing process that creates a product capable of slowly releasing HA and providing prolonged hydration and tissue remodeling. Skin hydration boosters, while also HA-based, generally have lower HA concentrations and are designed to primarily improve skin hydration superficially.

  • Duration and Spreadability: Profhilo's unique formulation allows it to spread evenly across the injection site, covering a larger area and providing a more diffuse improvement in skin quality. Hydration boosters tend to have a more localized effect, requiring multiple injections across the target area for comprehensive hydration.

  • Bio-stimulation: Beyond hydrating the skin, Profhilo stimulates the body's own HA production and enhances the formation of collagen and elastin, leading to significant improvements in skin texture, elasticity, and firmness over time. While skin hydration boosters improve moisture levels in the skin, they may not offer the same level of bio-stimulation and long-term tissue remodeling.

Ideal Candidates for Profhilo

Profhilo is an innovative skin remodeling treatment that has gained popularity for its ability to deliver significant improvements in skin texture, elasticity, and hydration using hyaluronic acid. The ideal candidates for Profhilo are those seeking to improve their skin's overall quality without the volumetric changes associated with traditional fillers. Here are some characteristics of ideal candidates for Profhilo:

1. Individuals with Early Signs of Aging

  • Profhilo is particularly beneficial for individuals starting to notice the early signs of aging, such as fine lines, slight loss of skin elasticity, and dullness. It effectively combats these issues by stimulating collagen and elastin production.

2. Those Seeking Improved Skin Hydration and Texture

  • People experiencing dry, dehydrated, or crepey skin can benefit from Profhilo's deeply hydrating properties, which enhance skin texture and give it a plumper, more radiant appearance.

3. Patients with Mild to Moderate Skin Laxity

  • Profhilo is ideal for individuals with mild to moderate skin laxity who are looking for a non-surgical solution to improve skin firmness and reduce sagging, particularly in the face, neck, hands, and décolletage areas.

4. People Looking for a Natural-Looking Rejuvenation

  • Individuals seeking subtle, natural-looking rejuvenation without drastic changes or augmentation will find Profhilo appealing. It enhances the skin's natural qualities rather than altering facial contours.

5. Those Interested in Preventative Anti-Aging Treatments

  • Younger individuals interested in maintaining their skin's youthfulness and delaying the onset of aging signs can benefit from Profhilo. It serves as an excellent preventative treatment by keeping the skin well-hydrated and stimulating its regenerative processes.

6. Individuals with All Skin Types

  • Profhilo is suitable for all skin types, including sensitive skin, because of its biocompatible nature. Hyaluronic acid is a substance naturally found in the body, minimizing the risk of adverse reactions.

7. People Looking for Minimal Downtime

  • Ideal candidates are those looking for an effective treatment with minimal to no downtime. Profhilo involves a quick procedure and usually allows patients to return to their normal activities immediately.

8. Patients Seeking a Complementary Treatment

  • Profhilo can be an ideal choice for individuals looking to complement other aesthetic treatments. It can be used in conjunction with treatments like Botox, dermal fillers, or laser therapy to achieve a comprehensive rejuvenation effect.

Who Should Avoid Profhilo?

  • Profhilo may not be suitable for individuals with active skin infections or conditions in the treatment area. Additionally, those with known allergies to hyaluronic acid products should avoid this treatment.

Profhilo offers a versatile solution for various skin concerns, particularly focusing on hydration, elasticity, and overall skin quality improvement. Consulting with a qualified healthcare professional is essential to determine if Profhilo is the right option based on individual skin conditions and aesthetic goals.

Preparing for a Profhilo Treatment

Preparing for a Profhilo treatment involves several steps to ensure the best possible outcome and minimize any potential side effects. Profhilo, known for its hydrating and bio-remodeling properties, can significantly improve skin texture, elasticity, and overall appearance with minimal downtime. Here’s how you can prepare for your Profhilo session:

1. Consultation

  • Initial Assessment: Schedule a consultation with a qualified practitioner who is experienced in administering Profhilo. Discuss your aesthetic goals, medical history, and any skin concerns to determine if Profhilo is the right treatment for you.
  • Treatment Plan: Your practitioner will develop a personalized treatment plan, including the number of sessions required and areas to be treated.

2. Medical History Review

  • Disclose Medical Conditions: Inform your practitioner about any medical conditions, allergies, skin diseases, or infections, as these may affect the treatment process or outcomes.
  • Medication and Supplements: Discuss any medications, supplements, or herbal treatments you are taking, especially those that may increase the risk of bruising or bleeding, such as aspirin, NSAIDs, or blood thinners.

3. Skin Care

  • Avoid Certain Products: Depending on your practitioner's advice, you may be asked to avoid using retinoids, exfoliating acids, or any other potentially irritating skin care products a few days before the treatment to reduce the risk of skin sensitivity.
  • Sun Protection: Protect your skin from excessive sun exposure before the treatment to avoid sunburn or skin damage, which could complicate the injection process.

4. Lifestyle Adjustments

  • Alcohol and Caffeine: It's advisable to avoid alcohol and reduce caffeine intake 24-48 hours before your treatment, as these can increase the risk of bruising.
  • Hydration: Stay well-hydrated before the procedure to support overall skin health.

5. Day of Treatment

  • Clean Skin: Come to your appointment with clean skin, free of makeup, moisturizers, or any other products.
  • Comfortable Clothing: Wear comfortable clothing and consider a top that allows easy access to the treatment areas if your neck or décolletage are being treated.

6. Post-Treatment Preparations

  • Arrange Transportation: While Profhilo has minimal downtime and side effects, if you're concerned about any discomfort or swelling, you might prefer not to drive immediately after the procedure, though this is typically not necessary.
  • Aftercare Products: Have gentle, non-irritating skincare products ready for use after the treatment, according to your practitioner's recommendations.

7. Realistic Expectations

  • Understand the Process: Familiarize yourself with what to expect during and after the treatment, including any potential side effects like temporary swelling or bruising and the typical timeline for seeing results.

By following these preparation steps, you can ensure a smoother Profhilo treatment experience and optimize your results. Always follow the specific advice given by your practitioner, as individual recommendations may vary based on your unique skin needs and health profile.

Articles About Profhilo Skin Booster

FAQs For Profhilo Skin Booster

What is Profhilo?

Profhilo is a hyaluronic acid (HA)-based product that is specifically engineered for skin bio-remodeling. It is not a dermal filler in the traditional sense but is used to improve skin tone, texture, hydration, and overall radiance. Profhilo has one of the highest concentrations of HA on the market, which helps to stimulate the production of collagen and elastin in the skin.

How does Profhilo work?

Profhilo works through a slow release of hyaluronic acid, which stimulates the production of four different types of collagen and elastin. This process, known as bio-remodeling, effectively rejuvenates the skin from within, improving skin laxity and restoring firmness.

What areas can be treated with Profhilo?

Profhilo is most commonly used to treat the face, but it can also be effective for rejuvenating the neck, décolletage, hands, arms, and knees. It is particularly popular for areas showing signs of skin aging and dehydration.

How many treatments are needed?

The standard Profhilo treatment protocol involves two sessions spaced four weeks apart. Some individuals may benefit from an additional third session, depending on their skin's condition and desired outcomes. Maintenance sessions every 6 months are recommended to sustain the results.